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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It can also be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports.
PEG-based PROTAC linker
Can be used in the synthesis of PROTACs
Can be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports
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Azido-PEG3-SS-PEG3-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent containing an azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules or strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Click chemistry reagent containing an azide group
Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups
Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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Aminooxy-PEG3-azide is a bifunctional PEG3 linker reagent containing an aminooxy group and an azide group, used for bioconjugation in ADC and PROTAC synthesis and for click chemistry conjugations.
Contains an aminooxy group for oxime ligation.
Contains an azide group for CuAAC and SPAAC click chemistry.
Three-unit PEG spacer provides solubility and flexibility.
High purity suitable for research applications.
Stable when stored at -20°C in pure form.
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Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag for the purification of recombinant proteins. It is a click chemistry reagent that contains an azide group. It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups, or strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Multifunctional fusion tag for the purification of recombinant proteins
Click chemistry reagent
Contains an azide group
Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) reaction with molecules containing alkyne groups
Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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Calcein tetraethyl ester, also known as Fluorexon tetraethyl ester, is a fluorescent dye utilized in biological applications. Its key characteristic is its ability to be transported through the cellular membrane into live cells. This property makes it valuable for assessing cell viability and for the short-term labeling of cells.
Effective for live cell studies: Its cell-permeable nature allows for direct application in living systems without damaging cell integrity.
Versatile in research: Can be used for various analyses including cell function, in vivo imaging, and cell staining.
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APN-PEG5-VC-PAB-MMAE is a drug-linker conjugate that is part of INA03, a transferrin-competitive antibody-drug conjugate against CD71. It is intended for research use only, and MedChemExpress does not sell to patients.
Drug-linker conjugate
Part of INA03 (a transferrin-competitive antibody-drug conjugate against CD71)
For research use only
Available in various quantities
Purity: 95.19%
Storage: -20°C, protect from light
Soluble in DMSO
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Calcein tetraethyl ester is a fluorescent dye used in biology for testing cell viability and short-term cell labeling. It can be transported through the cellular membrane into live cells.
Molecular weight: 734.75
Formula: C38H42N2O13
Appearance: Solid
Color: Light yellow to yellow
Emission (Em): 515
Excitation (Ex): 489
Solubility in DMSO: 25 mg/mL
Insolubility in H2O: < 0.1 mg/mL
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Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker designed for synthesizing PROTACs. It features an Azide group, enabling click chemistry reactions like copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
Can be used in the synthesis of PROTACs
Contains an Azide group for click chemistry reactions
Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups
Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs and has applications in cancer-programmed cell death.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Applications in cancer-programmed cell death
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Azido-PEG3-propionic acid tert-butyl ester is an azide-functionalized, Boc-protected PEG3 linker for bioconjugation. It acts as a cleavable three-unit PEG spacer and an azide reagent for click chemistry, suitable for assembling antibody-drug conjugates and PROTACs.
Azide-functionalized Boc-protected PEG3 linker.
Cleavable three-unit PEG spacer for ADC and PROTAC synthesis.
Suitable for CuAAC and SPAAC click chemistry.
Purity ≥98.0%.
Molecular weight 303.35 g/mol; formula C13H25N3O5.
Appearance colorless to light yellow liquid; follow storage recommendations.
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Tos-PEG3 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
Utilized in the synthesis of PROTACs.
Can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
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Azido-PEG5-azide is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a versatile click chemistry reagent, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
Used in the synthesis of PROTACs
Functions as a click chemistry reagent
Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
For research use only
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